Bioactivity:

G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM). G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.

CAS nr:

1346669-54-2

Purity:

98%

Molecular Weight:

527,64

SMILES:

CN(C1=O)C=C(C2=CC=CC(N3C(C(SC4=C5CC(C)(C)C4)=C5CC3)=O)=C2CO)C=C1NC6=CC=NC=N6

Formula:

C29H29N5O3S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK