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Bioactivity:
(R)-GNE-140 is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.
CAS nr:
2003234-63-5
Purity:
98%
Molecular Weight:
499,04
SMILES:
OC1=C(Sc2ccccc2Cl)C(=O)N[C@@](C1)(c1cccs1)c1ccc(cc1)N1CCOCC1
Formula:
C25H23ClN2O3S2
Pathway:
Metabolism
Target:
Dehydrogenase