Bioactivity:

BETd-260 is a potent degrader of BET based on PROTAC technology, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line.

CAS nr:

2093388-62-4

Purity:

98%

Molecular Weight:

798,89

SMILES:

CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCCCCC4=CC=CC5=C4CN(C6C(NC(CC6)=O)=O)C5=O)=O)=NC7=C3C8=CC(OC)=C(C9=C(C)ON=C9C)C=C8N7

Formula:

C43H46N10O6

Pathway:

Chromatin/Epigenetic,Others

Target:

Epigenetic Reader Domain,Others