Bioactivity:

PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 _M.�PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transge

CAS nr:

4079-26-9

Purity:

98%

Molecular Weight:

237,32

SMILES:

C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24

Formula:

C15H11NS

Pathway:

Autophagy,Apoptosis,Metabolism,Cell Cycle/Checkpoint

Target:

Autophagy,Ferroptosis,Lipoxygenase,Ferroptosis