Bioactivity:

RO 4938581 is an effective and selective agonist of GABAA _5 inverse (Ki: 4.6 nM for GABAA _5_3_2a, and shows a lower affinity at _1_3_2a, _2_3_2a, _3_3_2a (Ki, 174, 185, 80 nM, respectively)).

CAS nr:

883093-10-5

Purity:

98%

Molecular Weight:

352,14

SMILES:

FC(C1=C2N(C3=CC=C(Br)C=C3C4=NC=NN4C2)C=N1)F

Formula:

C13H8BrF2N5

Pathway:

Membrane transporter/Ion channel,Neuroscience

Target:

GABA Receptor,GABA Receptor