Bioactivity:

Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.

CAS nr:

1369852-71-0

Purity:

98%

Molecular Weight:

596,76

SMILES:

Cc1c(C(NCC(NCC(F)(F)F)=O)=O)sc(C(C2)=NO[C@]2(C(F)(F)F)c(cc2Cl)cc(Cl)c2Cl)c1

Formula:

C20H14Cl3F6N3O3S

Pathway:

Membrane transporter/Ion channel,Neuroscience,Microbiology/Virology

Target:

GABA Receptor,GABA Receptor,Parasite