Bioactivity:

Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with

CAS nr:

56365-38-9

Purity:

98%

Molecular Weight:

316,26

SMILES:

COc1c(O)cc2oc(Oc3ccc(O)cc3)cc(=O)c2c1O

Formula:

C16H12O7

Pathway:

Immunology/Inflammation,Tyrosine Kinase/Adaptors,Angiogenesis,Apoptosis,Immunology/Inflammation,MAPK,MAPK,Stem Cells,JAK/STAT signaling,Proteases/Proteasome,GPCR/G Protein,Immunology/Inflammation,NF-_b,Apoptosis,Neuroscience,Immunology/Inflammation,DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Immunology/Inflammation,MAPK

Target:

NOS,VEGFR,VEGFR,TNF,Prostaglandin Receptor,JNK,MAPK,STAT,STAT,MMP,Prostaglandin Receptor,TLR,NF-_B,BCL,COX,COX,DNA/RNA Synthesis,DNA/RNA Synthesis,IL Receptor,ERK