Bioactivity:

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki: 0.6 nM) by targeting a threonine residue.

CAS nr:

1132709-14-8

Purity:

98%

Molecular Weight:

384,24

SMILES:

OB([C@H](NC([C@@H](NC(C1=NC=CN=C1)=O)CC2=CC=CC=C2)=O)CC(C)C)O

Formula:

C19H25BN4O4

Pathway:

Proteases/Proteasome,Ubiquitination

Target:

Proteasome,Proteasome