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P2X3 antagonist 34 T10560

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

P2X3 antagonist 34 is a selective and orally active antagonist of P2X3 homotrimeric receptor (IC50s: 25_nM, 92_nM, and 126_nM for the human, rat, and guinea pig P2X3 receptors). It has a strong anti-tussive effect.

CAS nr:

T10560

Purity:

98%

Molecular Weight:

456,49

SMILES:

O=C(OC)N1C[C@@H](CCC1)CC2=C(N=C3C=C(C=CN32)C)C4=C(C=C(C=C4F)C(NC)=O)F

Formula:

C24H26F2N4O3

Pathway:

Neuroscience

Target:

P2 Receptor