Bioactivity:

CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. C

CAS nr:

2206788-99-8

Purity:

98%

Molecular Weight:

511,45

SMILES:

ClC(C=C(Cl)C=C1)=C1[C@@H](C)N2N=C(C#N)C3=C2N=C(C4=CC[C@H](N5[C@H](CO)CCC5)[C@H](C)C4)C=N3

Formula:

C26H28Cl2N6O

Pathway:

Metabolism,Membrane transporter/Ion channel

Target:

Calcium Channel,Calcium Channel