Bioactivity:

iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.

CAS nr:

2410557-00-3

Purity:

98%

Molecular Weight:

886,96

SMILES:

O=C(NCC1)C2=CC(F)=CC3=C2C1=C(C4=CC=C(C=C4)CN(CCOCCOCCOCCOCCOCCOCCNC5=CC=CC(C(N6C7CCC(NC7=O)=O)=O)=C5C6=O)C)N3

Formula:

C46H55FN6O11

Pathway:

Others

Target:

Others