Bioactivity:

ARQ 069 (3.8-60 _M; for 2 hours) reduces the degree of phosphorylation of FGFR (predominantly FGFR2) in a concentration-dependent manner, without decreasing _-actin. ARQ 069 shows an affinity for FGFR2 of 5.2 _M. ARQ 069 inhibits FGFR phosphorylation in K

CAS nr:

1314021-57-2

Purity:

98%

Molecular Weight:

273,33

SMILES:

NC1=NC=C2C[C@@H](C3=CC=CC=C3)C4=CC=CC=C4C2=N1

Formula:

C18H15N3

Pathway:

Others

Target:

Others