Bioactivity:

NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 _M/1.3 _M, 0.4 _M and 2.2 _M, enter cells more readily than the 6-aminopurine-based inhibitors.

CAS nr:

220036-08-8

Purity:

98%

Molecular Weight:

251,28

SMILES:

NC1=NC(N)=C(N=O)C(OCC2CCCCC2)=N1

Formula:

C11H17N5O2

Pathway:

Cell Cycle/Checkpoint,PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair,PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair

Target:

CDK,ATM/ATR,ATM/ATR,DNA-PK,DNA-PK