Bioactivity:

PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.

CAS nr:

866206-55-5

Purity:

98%

Molecular Weight:

517,96

SMILES:

C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N.C(=C\C(=O)O)\C(=O)O

Formula:

C19H17ClFN5S�C4H4O4

Pathway:

GPCR/G Protein,Neuroscience

Target:

5-HT Receptor,5-HT Receptor