Bioactivity:

EML741 also inhibits DNMT1 (IC50, 3.1 _M), with no effect on DNMT3a or DNMT3b.�EML741 exhibits low cell toxicity, and is membrane permeable and blood-brain barrier penetrated.�EML741 is a histone lysine methyltransferase G9a/GLP inhibitor, with an IC50 of

CAS nr:

2328074-38-8

Purity:

98%

Molecular Weight:

523,75

SMILES:

COC1=C(OCCCN2CCCC2)C=C3N=C(C4CCCCC4)CN=C(NC5CCN(C(C)C)CC5)C3=C1

Formula:

C31H49N5O2

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase