Bioactivity:

Pemigatinib is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).

CAS nr:

1513857-77-6

Purity:

98%

Molecular Weight:

487,5

SMILES:

CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4

Formula:

C24H27F2N5O4

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

FGFR,FGFR