Bioactivity:

PF-3882845 also binds to the progesterone receptor (the binding IC50: 310 nM). PF-3882845 is a remarkably high affinity selective and orally efficacious mineralocorticoid receptor (MR binding IC50=2.7 nM) antagonist for hypertension and nephropathy.

CAS nr:

1023650-66-9

Purity:

98%

Molecular Weight:

419,9

SMILES:

N#CC1=CC=C(N2N=C(C(C=CC(C(O)=O)=C3)=C3CC4)[C@H]4[C@@H]2C5CCCC5)C=C1Cl

Formula:

C24H22ClN3O2

Pathway:

Others

Target:

Others