GSK-J1 T6847
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.
CAS nr:
1373422-53-7
Purity:
98%
Molecular Weight:
389,45
SMILES:
OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
Formula:
C22H23N5O2
Pathway:
Chromatin/Epigenetic
Target:
Histone Demethylase
