Bioactivity:

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)

CAS nr:

1268524-71-5

Purity:

98%

Molecular Weight:

456,99

SMILES:

CC1=C(C)C2=C(S1)N1C(C)=NN=C1[C@@H](CC(=O)OC(C)(C)C)N=C2C1=CC=C(Cl)C=C1

Formula:

C23H25ClN4O2S

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain