Bioactivity:

RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.

CAS nr:

919091-63-7

Purity:

98%

Molecular Weight:

365,34

SMILES:

[O-][N+](=O)c1ccc(\C=C2/CNC\C(=C/c3ccc(cc3)[N+]([O-])=O)C2=O)cc1

Formula:

C19H15N3O5

Pathway:

Ubiquitination,Cell Cycle/Checkpoint,Apoptosis,DNA Damage/DNA Repair

Target:

DUB,DUB,Apoptosis,DUB