Bioactivity:

PF-05221304 is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.

CAS nr:

1370448-25-1

Purity:

98%

Molecular Weight:

502,56

SMILES:

O=C(O)C1=CC=C(C2=NC(OC)=CC(C(N3CCC(C4)(CC3)CC5=C(N(C(C)C)N=C5)C4=O)=O)=C2)C=C1

Formula:

C28H30N4O5

Pathway:

Proteases/Proteasome,Metabolism

Target:

Acetyl-CoA Carboxylase,Acetyl-CoA Carboxylase