Bioactivity:

BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.

CAS nr:

2162961-71-7

Purity:

98%

Molecular Weight:

527,42

SMILES:

O=C(N1C[C@]2([H])[C@H](CNC(C3=CC=C(NN=N4)C4=C3)=O)[C@]2([H])C1)OCC5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5

Formula:

C23H19F6N5O3

Pathway:

Others

Target:

Others