Bioactivity:

SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 _M, 0.65 _M, 0.3 _M,

CAS nr:

1832686-44-8

Purity:

98%

Molecular Weight:

533,6

SMILES:

OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N

Formula:

C27H34F3N5O3

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Met/HGFR