Bioactivity:

Necrostatin 2 is an effective necroptosis inhibitor. Necrostatin 2 is also a RIPK1 inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-_ is 0.05 _M.

CAS nr:

852391-19-6

Purity:

98%

Molecular Weight:

277,71

SMILES:

ClC1=C2C(C(C[C@@H]3C(N(C)C(N3)=O)=O)=CN2)=CC=C1

Formula:

C13H12ClN3O2

Pathway:

Others

Target:

Others