Bioactivity:

DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 _M and 0.18 _M, respectively. DHODH-IN-4 has antimalarial activity.

CAS nr:

1148125-93-2

Purity:

98%

Molecular Weight:

347,2

SMILES:

C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2Cl)C=C1Cl)=O

Formula:

C17H12Cl2N2O2

Pathway:

Others

Target:

Others