Bioactivity:

SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 _M respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of

CAS nr:

5812/7/7

Purity:

98%

Molecular Weight:

264,33

SMILES:

CN(C)c1ccc(C=C2C(=O)Nc3ccccc23)cc1

Formula:

C17H16N2O

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis

Target:

PDGFR,PDGFR,VEGFR,VEGFR