Bioactivity:

PFI-2 hydrochloride is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.

CAS nr:

1627607-87-7

Purity:

98%

Molecular Weight:

535,98

SMILES:

Cl.Fc1cc(cc2CCNCc12)S(=O)(=O)N[C@H](Cc1cccc(c1)C(F)(F)F)C(=O)N1CCCC1

Formula:

C23H26ClF4N3O3S

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase