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Bioactivity:
AC708 is a small molecule CSF1R inhibitor that effectively inhibits CSF1R phosphorylation mediated by CSF-1 (IC50 = 26 nM) and IL-34 (IC50 = 33 nM). It also inhibited the activity of growth factor-dependent cells cultured in CSF-1 (IC50 = 38 nM) or IL-34
CAS nr:
T29542
Purity:
98%
Molecular Weight:
SMILES:
NA
Formula:
Pathway:
Target: