Bioactivity:

Bigelovin is a selective retinoid X receptor _ agonist.�Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a potent cytotoxic sesquiterpene lactone

CAS nr:

3668-14-2

Purity:

98%

Molecular Weight:

304,34

SMILES:

C[C@H](C[C@@H]([C@H]([C@@H]([C@]12C)OC(C)=O)C3=C)OC3=O)[C@@H]2C=CC1=O

Formula:

C17H20O5

Pathway:

Metabolism,NF-_b,Metabolism,Immunology/Inflammation,Autophagy,Metabolism,Apoptosis

Target:

RAR/RXR�,Reactive Oxygen Species,Reactive Oxygen Species,Reactive Oxygen Species,Autophagy,Retinoid Receptor,Apoptosis