Bioactivity:

1G244 is a potent DPP8/9 inhibitor with IC50s of 12 nM and 84 nM, respectively. 1G244 does not inhibit DPPIV and DPPII. 1G244 induces apoptosis in multiple myeloma cells and has anti-myeloma effects[1][2].

CAS nr:

847928-32-9

Purity:

98%

Molecular Weight:

504,57

SMILES:

O=C(N1CC2=C(C=CC=C2)C1)[C@@H](N)CC(N3CCN(C(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3)=O

Formula:

C29H30F2N4O2

Pathway:

Others

Target:

Others