Bioactivity:

OXSI-2 is an Syk Inhibitor. OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux. OXSI-2 inhibits inflammasome assembly, caspase-1 activation, IL-1_ processing and release, mitochondrial ROS generation, and

CAS nr:

622387-85-3

Purity:

98%

Molecular Weight:

353,4

SMILES:

O=S(C1=CC2=C(NC(/C2=C/C3=CN(C)C4=C3C=CC=C4)=O)C=C1)(N)=O

Formula:

C18H15N3O3S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

Syk,Syk