Bioactivity:

Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 _M and 0.93 _M, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.

CAS nr:

355025-13-7

Purity:

98%

Molecular Weight:

488,98

SMILES:

COC(=O)CCSCC1=CC=C(C=C1)C1=C(NC(=O)OC(C)C2=C(Cl)C=CC=C2)C(C)=NO1

Formula:

C24H25ClN2O5S

Pathway:

GPCR/G Protein,GPCR/G Protein

Target:

LPL Receptor,LPA Receptor