Bioactivity:

SU11274(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFR_, EGFR or Tie2.

CAS nr:

658084-23-2

Purity:

98%

Molecular Weight:

568,09

SMILES:

CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1

Formula:

C28H30ClN5O4S

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Autophagy,Apoptosis,Cell Cycle/Checkpoint,Tyrosine Kinase/Adaptors

Target:

VEGFR,VEGFR,FGFR,FGFR,Autophagy,Apoptosis,CDK,c-Met/HGFR