Bioactivity:

PKR-IN-C51 is an inhibitor of protein kinase R. It acts by correcting the aberrant splicing of MBNL1-dependent pre-mRNAs in DM1 cells without affecting the splicing pattern in normal non-DM1 cells.

CAS nr:

1314594-23-4

Purity:

98%

Molecular Weight:

367,45

SMILES:

CC(N1)=C(C2=NC(NCCC3=CNC4=C3C=CC=C4)=NC=C2)C5=C1C=CC=C5

Formula:

C23H21N5

Pathway:

Target: