Bioactivity:

Grapiprant is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM).

CAS nr:

415903-37-6

Purity:

98%

Molecular Weight:

491,6

SMILES:

CCc1nc(c(C)nc(C)c2)c2n1-c1ccc(CCNC(NS(c2ccc(C)cc2)(=O)=O)=O)cc1

Formula:

C26H29N5O3S

Pathway:

GPCR/G Protein,Immunology/Inflammation

Target:

Prostaglandin Receptor,Prostaglandin Receptor