TargetMol Chemicals

TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

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(E)-SIS3 T3636

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

SIS3, a selective Smad3 inhibitor, can attenuate TGF-_1-dependent Smad3 phosphorylation and DNA binding. It has no effect on p38 MAPK, Smad2, ERK or PI3K signaling. It also inhibits TGF-_1-induced myofibroblast differentiation of dermal fibroblasts and in

CAS nr:

521984-48-5

Purity:

98%

Molecular Weight:

489,99

SMILES:

Cn1c(c(c2c1nccc2)/C=C/C(=O)N1CCc2cc(c(cc2C1)OC)OC)c1ccccc1.Cl

Formula:

C28H27N3O3�HCl

Pathway:

Stem Cells

Target:

TGF-beta/Smad