Bioactivity:

ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.

CAS nr:

1035688-66-4

Purity:

98%

Molecular Weight:

356,32

SMILES:

O=C(C1=CC=CN=C1NC2=C(F)C=C(C3=CC=CC(OC)=C3)C=C2F)O

Formula:

C19H14F2N2O3

Pathway:

Apoptosis,Metabolism,DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

Apoptosis,Dehydrogenase,DNA/RNA Synthesis,DNA/RNA Synthesis