Bioactivity:

IRL 2500 is an effective antagonist of the Endothelin receptor. IRL 2500 suppresses ETB�receptor-mediated blood pressure increase and renal vascular resistance in rats�in vivo. IRL 2500 displays (IC50:1.3 and 94 nM for ETB�and ETA�receptors, respectively)

CAS nr:

169545-27-1

Purity:

98%

Molecular Weight:

573,68

SMILES:

O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC([C@@H](CC3=CC=C(C4=CC=CC=C4)C=C3)N(C(C5=CC(C)=CC(C)=C5)=O)C)=O

Formula:

C36H35N3O4

Pathway:

Others

Target:

Others