Bioactivity:

ATX inhibitor 5 is an orally active autotaxin (ATX) inhibitor (IC50: 15.3 nM). It has an anti-hepatofibrosis effect and reduces CCl4-induced hepatic fibrosis level prominently.

CAS nr:

2402772-45-4

Purity:

98%

Molecular Weight:

474,87

SMILES:

O=C(N/N=C/C1=CC=C(Cl)C=C1)N(C2)CCC3=C2C(NC4=CC=CC(C(F)(F)F)=C4)=NC=N3

Formula:

C22H18ClF3N6O

Pathway:

Metabolism

Target:

PDE