Bioactivity:

PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR(CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-induced hypernociception in rats.

CAS nr:

219639-75-5

Purity:

98%

Molecular Weight:

896,11

SMILES:

N=C(NCCC[C@H](NC([C@@H](NC([C@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC(C)=O)CC2=CC=CC=C2)=O)CCCN3)=O)=O)CC4CCCCC4)=O)CC5=CNC6=C5C=CC=C6)=O)C3=O)N

Formula:

C47H65N11O7

Pathway:

Target: