TargetMol Chemicals

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GNF-5 T1803

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22ﾱ0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.

CAS nr:

778277-15-9

Purity:

98%

Molecular Weight:

418,37

SMILES:

c1cc(cc(c1)C(=O)NCCO)c1cc(ncn1)Nc1ccc(cc1)OC(F)(F)F

Formula:

C20H17F3N4O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Microbiology/Virology

Target:

Bcr-Abl,Bcr-Abl,Bcr-Abl,SARS-CoV