Bioactivity:

DAPT is a novel _-secretase inhibitor which reduces the A_ production (IC50: 20 nM in HEK 293 cells) and A_42 levels (IC50: 200 nM).

CAS nr:

208255-80-5

Purity:

98%

Molecular Weight:

432,46

SMILES:

C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1

Formula:

C23H26F2N2O4

Pathway:

Stem Cells,Proteases/Proteasome,Neuroscience,Autophagy,Apoptosis,Neuroscience

Target:

Gamma-secretase,Gamma-secretase,Gamma-secretase,Autophagy,Apoptosis,Beta Amyloid