Bioactivity:

BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.

CAS nr:

896705-16-1

Purity:

98%

Molecular Weight:

360,41

SMILES:

CN(C)CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O

Formula:

C21H20N4O2

Pathway:

DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

DNA/RNA Synthesis,DNA/RNA Synthesis