Semaxinib T2064
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Semaxanib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 _M), 20-fold more selective for VEGFR than PDGFR_, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular
CAS nr:
204005-46-9
Purity:
98%
Molecular Weight:
238,28
SMILES:
Cc3cc(C)nc3C=C1c2ccccc2NC1=O
Formula:
C15H14N2O
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis
Target:
VEGFR,VEGFR