Bioactivity:

L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D2 (Ki: 960 nM) and D3 (Ki: 2300 nM) receptors affinity.

CAS nr:

158985-00-3

Purity:

98%

Molecular Weight:

326,82

SMILES:

ClC(C=C1)=CC=C1N(CC2)CCN2CC3=CNC4=NC=CC=C43

Formula:

C18H19ClN4

Pathway:

Neuroscience,GPCR/G Protein

Target:

Dopamine Receptor,Dopamine Receptor