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Bioactivity:
FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
CAS nr:
1232030-35-1
Purity:
98%
Molecular Weight:
513,39
SMILES:
CCn1c2nc(Nc3ccc(N4CCNCC4)c(F)c3)ncc2cc(-c2ccc(Cl)cc2Cl)c1=O
Formula:
C25H23Cl2FN6O
Pathway:
Cytoskeletal Signaling
Target:
PAK