Bioactivity:

Ranirestat effective and orally active aldose reductase inhibitor ( IC50s: 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively and a Ki: 0.38 nM for recombinant human AR). Ranirestat has a neuroprotective effect on diabetic retinas.

CAS nr:

147254-64-6

Purity:

98%

Molecular Weight:

420,19

SMILES:

O=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O

Formula:

C17H11BrFN3O4

Pathway:

Others

Target:

Others