Bioactivity:

GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.

CAS nr:

220904-83-6

Purity:

98%

Molecular Weight:

520,94

SMILES:

c1cc2c(cc1I)/C(=C/c1cc(c(c(c1)Br)O)Br)/C(=O)N2

Formula:

C15H8Br2INO2

Pathway:

MAPK,Apoptosis

Target:

Raf,Apoptosis