Bioactivity:

HPN-01 is a selective IKK inhibitor (pIC50s: 6.4, 7.0, and <4.8 for IKK-_, IKK-_, and IKK-_). HPN-01 displays greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, ErbB2, EGFR, GSK3_, Src, PLK1, and VEGFR-2.

CAS nr:

928655-63-4

Purity:

98%

Molecular Weight:

401,87

SMILES:

O=C(C1=C(N)C(C2=CC=C(S(=O)(N)=O)C=C2)=CC(C3=CC=C(Cl)C=C3)=C1)N

Formula:

C19H16ClN3O3S

Pathway:

Others

Target:

Others