Bioactivity:

Eltanexor is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leuk

CAS nr:

1642300-52-4

Purity:

98%

Molecular Weight:

428,29

SMILES:

NC(/C(/c1cncnc1)=C/n1nc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)nc1)=O

Formula:

C17H10F6N6O

Pathway:

Others

Target:

Others